Neurosarcoidosis and Associated Neuropsychological Sequelae: A Rare Case Of Isolated Intracranial Involvement

Abstract

We present a case study of an individual diagnosed with isolated neurosarcoidosis, a rare granulomatous condition of unknown aetiology. Although the extant medical literature on this disease is adequate, no study has focused on the neuropsychological sequelae involved with such an inflammatory disorder. The case described herein is of a 57-year-old woman who participated in a neuropsychological evaluation following complaints of recurring cognitive difficulties. Results of the assessment revealed moderate difficulties in effortful word retrieval and recall of unstructured verbal information, as well as some mild mental rigidity, slowing, and subtle difficulties with attention. Her neuropsychological profile is discussed in terms of neuroanatomic lesion localization and clinical diagnostic implications.

Keywords:

• Neurosarcoidosis
• Neuropsychological sequelae
• Review
• Frontal lobe
• Basal ganglia

Acknowledgments

The author gratefully acknowledges Dr. A. Feinstein for his suggestions for acquiring clinical documents and Dr. L. Leach for his comments on the manuscript.