Abstract
Depression frequently co-occurs with HIV infection and can result in self-reported overestimates of cognitive deficits. Conversely, genuine cognitive dysfunction can lead to an under-appreciation of cognitive deficits. The degree to which depression and cognition influence self-report of capacity for instrumental activities of daily living (IADLs) requires further investigation. This study examined the effects of depression and cognitive deficits on self-appraisal of functional competence among 107 HIV-infected adults. As hypothesized, higher levels of depression were found among those who over-reported problems in medication management, driving, and cognition when compared to those who under-reported or provided accurate self-assessments. In contrast, genuine cognitive dysfunction was predictive of under-reporting of functional deficits. Together, these results suggest that over-reliance on self-reported functional status poses risk for error when diagnoses require documentation of both cognitive impairment and associated functional disability in everyday life.
Acknowledgments
This study was funded by the VA merit review award entitled: Aging in HIV/AIDS: Neurocognitive Sequelae and Functional Consequences (PI: Charles Hinkin, Ph.D.). Special thanks to members of our laboratory Jiah Jang, Michelle Kim, Melissa Choi, Gabriel Waterman, Laurie Chew, and Arielle Newman who assisted with participant recruitment and data collection.