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Abstract
OBJECTIVE: To assess the safety and efficacy of the implantation of Paclitaxel Eluting Stents (PES) for de novo, non‐flow limiting lesions. METHODS AND RESULTS: We assessed the 12‐month occurrence of major adverse cardiac events (MACE) in 21 patients (4% of the total population treated in a ‘real world’ registry) with 22 non‐significant coronary narrowings treated with PES. The following criteria had to be met: (1) the lesion was de novo; (2) the location was non‐ostial, and not a bifurcation lesion; (3) the diameter stenosis by quantitative coronary angiography (QCA) was <50%; (4) there was no visible thrombus and (5) the lesion was not located in an angiographically diffusely diseased segment. Procedural success rate was 100% without any periprocedural myocardial infarction. After a mean follow‐up of 407.33±53 (range: 344–498) days the overall MACE‐free survival was 95.2%. Freedom from target revascularization was 95.2%. CONCLUSIONS: The result of this non‐randomized observational study suggests that the implantation of PES for de novo, non‐significant lesions appears most probably safe and effective.