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Review

Technological advancements and future perspectives in breast cancer radiation therapy

, , , , , , , , , , , ORCID Icon & show all
Pages 407-419 | Received 13 Sep 2022, Accepted 21 Mar 2023, Published online: 28 Mar 2023
 

ABSTRACT

Introduction

Breast cancer is still one of the most common tumors worldwide and radiation therapy has a central role in the oncological pathway. Several technological options are now available with the aim to improve therapeutic index, target definition, and patient selection.

Areas covered

In this review, we summarize current available technologies in the management of breast cancer. These advances can support the prescription of postoperative partial breast cancer treatment and preoperative stereotactic partial breast irradiation. Moreover, image-guided radiotherapy is crucial for high-quality radiation treatments. Additionally, the recent development of hybrid magnetic resonance linear accelerator can impact target volume outline procedure, adaptive planning and radiomics. Finally, artificial intelligence represents the new frontier in medicine, supporting clinicians in target definition, patient selection, and treatment planning.

Expert opinion

In patients with breast cancer the overall level of evidence about new technologies is still low even if some advances are potentially very interesting to further development.

Declaration of interest

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

Reviewer disclosures

Peer reviewers on this manuscript have no relevant financial or other relationships to disclose.

Author contribution statement

Conceptualization, AF and NGL.; methodology, AF, IM and NGL; data curation, AF, FDR, MCDS, IM, BM, NGL; writing – original draft preparation, AF, FDR, MCDS, IM, BM, EDA, DD, VF, ELR, PF, CS, LB, NGL; writing – review and editing, AF, FDR, MCDS, IM, BM, EDA, DD, VF, ELR, PF, CS, LB, NGL. All authors have read and agreed to the published version of the manuscript.

Supplementary material

Supplemental data for this article can be accessed online at https://doi.org/10.1080/14737140.2023.2195167

Additional information

Funding

This paper received no funding.

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