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Expert Review of Vaccines Volume 21, 2022 - Issue 2
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Original Research

Is vaccination necessary for COVID-19 patients? A retrospective cohort study investigating reinfection rates and symptomatology in a tertiary hospital

Ferhat Arslana Department of Infectious Diseases and Clinical Microbiology, Istanbul Medeniyet University, Istanbul, TurkeyCorrespondence[email protected]
,
Burcu Isık Gorenb Department of Infectious Diseases and Clinical Microbiology, Prof. Dr. Suleyman Yalçın, Goztepe City Hospital, Istanbul, Turkey
,
Begumhan Baysalc Department of Radiology, Prof. Dr. Suleyman Yalçın, Goztepe City Hospital, Istanbul, Turkey
&
Haluk Vahaboğlua Department of Infectious Diseases and Clinical Microbiology, Istanbul Medeniyet University, Istanbul, TurkeyORCID Iconhttps://orcid.org/0000-0001-8217-1767
ORCID Icon
Pages 249-252 | Received 16 Aug 2021, Accepted 26 Nov 2021, Published online: 07 Dec 2021
 
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ABSTRACT

Background

Durability of immune response by the COVID-19 natural infection and the necessity of vaccines in recovered patients are important inquiries for the healthcare provider.

Research Design and Methods

Here, we investigated the characteristics and the rate of cases with reinfection that have been admitted to our tertiary hospital.

Results

A total of 119985 patients were applied between March 2020 and May 2021. Of these patients, 32607 (27%, 32,607/119985) tested positive. A total of 27 (0.08%, 27/32607) patients were found to be reinfected beyond 90 days. Only one of these reinfected patients (0.003, 1/32607) had novel COVID-19 pneumonia and was hospitalized for the second time. Other 26 reinfected patients were followed up as outpatients.

Conclusions

COVID-19 reinfection is extremely rare. However, the reinfection may be severe in patients with immune deficiency. Healthcare providers may prioritize uninfected and immune-compromised patients for vaccination.

Declaration of Interests

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

Reviewer disclosures

Peer reviewers on this manuscript have no relevant financial or other relationships to disclose.

Ethical statement

Ethical approval was obtained from the local Ethics Committee of Istanbul Medeniyet University (#2021/0406). The ethics committee approved of patient consent waiver.

Author contributions

F Arslan, conceptualizing, investigating and writing; H Vahaboglu, supervising and editing; B Baysal & B Isik Goren, data collection.

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