Comparing the efficiency of Er,Cr:YSGG laser and diode laser on human β-defensin-1 and IL-1β levels during the treatment of generalized aggressive periodontitis and chronic periodontitis

ABSTRACT

Background: The aim of this study is to determine the suitability of the Er,Cr:YSGG and 940 ± 15-nm diode laser for the treatment of generalized aggressive periodontitis and chronic periodontitis by measuring the levels of human β-defensin-1 and IL-1β. Patients and Methods: A total of 26 patients were included in this study. The study was designed as a “split-mouth” experiment. We performed scaling and root planing in the right maxillary quadrant, scaling and root planning + Er,Cr:YSGG laser in the left maxillary quadrant, scaling and root planning + 940 ± 15-nm diode laser in the left mandibular quadrant, and only scaling and root planing in the right mandibular quadrant. The presence of human β-defensin-1 and IL-1β was analyzed with an ELISA. Results: When the baseline and post-treatment human β-defensin-1 levels and IL-1β levels of the study groups were evaluated, a decrease in human β-defensin-1 and IL-1β were observed in the quadrant where the Er,Cr:YSGG laser was applied in both the generalized aggressive periodontitis group and the chronic periodontitis group. Conclusions: The use of the Er,Cr:YSGG laser at non-surgical periodontal treatment decreased both IL-1β and human β-defensin-1 levels. It is likely that Er,Cr:YSGG laser is more suitable for the treatment of generalized aggressive periodontitis and chronic periodontitis.

KEYWORDS:

• Diode laser
• ErCr:YSGG laser
• human β-defensin-1
• IL-1β

Funding

This study was self-funded by the authors and by The University of Yuzuncu Yil University (Committee of Research 2014-SBE-D015).

Acknowledgments

The authors thank the School of Dentistry, Yuzuncu Yil University, for their support.

Additional information

Funding

This study was self-funded by the authors and by The University of Yuzuncu Yil University (Committee of Research 2014-SBE-D015).