Advanced search
Publication Cover
The Journal of Maternal-Fetal & Neonatal Medicine Volume 34, 2021 - Issue 10
Submit an article Journal homepage
46
Views
0
CrossRef citations to date
0
Altmetric
Short Report

Maternal peripheral blood CD34+ cells for prediction of fetal kidney malformations: results from a case-control analysis

Domenico Giordanoa Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood “G. Barresi”, University of Messina, Messina, Italy
,
Valeria Cernarob Department of Experimental Medicine, University of Messina, Messina, Italy
,
Mariagrazia Scilipotic Department of Human Pathology in Adulthood and Childhood “G. Barresi”, Unit of Pediatric Nephrology and Rheumatology, University of Messina, Messina, Italy
,
Sonia Cosentinod Department of Health Sciences, Renal Unit, Magna Graecia University, Catanzaro, Italy
,
Ramona Inferrerac Department of Human Pathology in Adulthood and Childhood “G. Barresi”, Unit of Pediatric Nephrology and Rheumatology, University of Messina, Messina, Italy
,
Jlenia Frestac Department of Human Pathology in Adulthood and Childhood “G. Barresi”, Unit of Pediatric Nephrology and Rheumatology, University of Messina, Messina, Italy
,
Michele Andreuccid Department of Health Sciences, Renal Unit, Magna Graecia University, Catanzaro, Italy
,
Giovanni Contic Department of Human Pathology in Adulthood and Childhood “G. Barresi”, Unit of Pediatric Nephrology and Rheumatology, University of Messina, Messina, Italy
,
Michele Buemib Department of Experimental Medicine, University of Messina, Messina, Italy
,
Rosario D’Annaa Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood “G. Barresi”, University of Messina, Messina, Italy
&
Giuseppe Coppolinod Department of Health Sciences, Renal Unit, Magna Graecia University, Catanzaro, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8000-0681
ORCID Icon show all
Pages 1679-1682 | Received 18 Apr 2019, Accepted 16 Jul 2019, Published online: 29 Jul 2019
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Purpose

To evaluate the relation between CD34+ cells count in maternal blood and potential development of fetal congenital renal abnormalities.

Materials and methods

We enrolled 16 women that gave birth to newborns carrying congenital renal malformations over a 3-year period and 48 women with uncomplicated pregnancies (controls) in a 1:3 ratio (three controls per case).

Results

CD34+ cells in the maternal peripheral blood were significantly lower in the group of women who gave birth to newborns carrying congenital renal malformations compared to the controls (p < .0001).

Conclusions

CD34+ cells in maternal blood could be validated as a potential marker to predict the development of possible kidney malformations.

Disclosure statement

No potential conflict of interest was reported by the authors.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later
PDF download + Online access
  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart
* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.