318
Views
1
CrossRef citations to date
0
Altmetric
Original Articles

The effect of delayed cord clamping on blood sugar levels on 34–36 week neonates exposed to late preterm antenatal steroids

, , & ORCID Icon
Pages 3587-3594 | Received 17 Jul 2020, Accepted 30 Sep 2020, Published online: 12 Oct 2020
 

Abstract

Objective

Neonatal hypoglycemia is a known side effect of antenatal betamethasone (BMZ) given for fetal maturation. We sought to investigate if delayed cord clamping (DCC) has an impact on neonatal hypoglycemia induced by antenatal late preterm BMZ administration.

Material and methods

Retrospective cohort study (January 2019–May 2019) of pregnancies undergoing delivery at 34–0/7 to 36–6/7 weeks at a single center included in two groups: DCC + BMZ and BMZ-only (no DCC). The primary outcome was the occurrence of neonatal hypoglycemia at the first hour after delivery.

Results

A total of 62/188, 32.98% (DCC + BMZ group) and 45/100, 45% (DCC-only group) infants presented with hypoglycemia at 1-h after birth (adjusted p = .06; OR 0.73, 95% CI 0.54–1.01). When stratified according to gestational age at delivery, DCC was associated with a 46% reduction in the occurrence of neonatal hypoglycemia among those born at 35–0/7 to 35–6/7 weeks (adjusted p = .033; OR 0.54, 95% CI 0.33–0.88) and 35% reduction among those born at 36–0/7 to 36–67 weeks (adjusted p = .046; OR 0.65, 95% CI 0.43–0.97).

Conclusion

In our cohort, delayed cord clamping in infants receiving late preterm BMZ born between 35–0/7 and 36–6/7 weeks’ gestation protects from early neonatal hypoglycemia.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

Funding for this study was provided by internal funds allocated to the collaboration by both Children's National and Inova Health Systems.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access
  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart
* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.