Synthesis, antifungal, and phytotoxic effects of some benzopyrone derivatives

Abstract

Syntheses of benzopyrones 1, 13, and their derivatives, as well as their phytotoxic (in vitro) and antifungal (in vitro) screening was carried out. Compounds 2, 7, 8, and 10 showed significant phytotoxic activity, whereas 3, 8, 10, and 12 exhibited significant antifungal (in vitro) activity.

Keywords:

• Synthesis
• Benzopyrones
• Phytotoxicity
• Fungicidal activity

Acknowledgment

This work was financially supported by the Pakistan Science Foundation (Grant No. SKU/CHEM/372).

Notes

*Standard Drugs MIC µg/mL; A = Miconazole (70 µg/mL), B = Miconazole (110.8 µg/mL), C = Amphotericin B (20 µg/mL), D = Miconazole (98.4 µg/mL), E = Miconazole (73.25 µg/mL), F = Miconazole (110.8 µg/mL).