Marmenol: A 7-geranyloxycoumarin from the leaves of Aegle marmelos corr.

Abstract

A new 7-geranyloxycoumarin [7-(2,6-dihydroxy-7-methoxy-7-methyl-3-octaenyloxy) coumarin] named marmenol (1) has been isolated from the leaves of methanolic extract ofAegle marmelosbelonging to the family Rutaceae. In addition to marmenol, several known compounds have also been obtained for the first time from the same source. They include: praealtin D, trans-cinnamic acid, valencic acid, 4-methoxy benzoic acid, betulinic acid, N-p-cis- and trans-coumaroyltyramine, montanine, and rutaretin. The structures of marmenol and known constituents were established with the help of NMR spectroscopy. However, structure of1was further confirmed via 2-D NMR experiments.

Keywords:

• Aegle marmelos
• Marmenol
• Rutaceae
• Leaves
• 7-Geranyloxycoumarin
• Spectroscopy
• Structure elucidation