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Natural Product Research
Formerly Natural Product Letters
Volume 21, 2007 - Issue 7
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Original Articles

A new fatty acid ester of triterpenoid from Celastrus rosthornianus with anti-tumor activitives

Pages 669-674 | Received 21 Nov 2006, Accepted 04 May 2007, Published online: 20 Jun 2007
 

Abstract

The methanol extract of the stalks of Celastrus rosthornianus Loes. afforded a new fatty acid ester of triterpene: 1β,3β-dihydroxy-olean-9(11),12-dienyl-3-palmitate (1), and three known compounds β-amyrin palmitate (2), 3β-hydroxy-11-oxo-olean-12-enyl-3-palmitate (3) and lupeol palmitate (4). Their structures were established by HRMS, 1D and 2D NMR experiments, as well as, by chemical degradation. The new compound showed cytotoxicity against human cervical squamous carcinoma (Hela) cells.

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