The green approaches for the synthesis of N-dehydroabietic α-aminophosphonates

Abstract

Three kinds of O,O-diethyl N-dehydroabietic aminoarylmethylphosphonates were synthesized from natural product derivatives by two steps of solvent-free reactions through imines intermediates and their structures were characterized by IR, ¹H NMR and ³¹P NMR spectroscopy. The solvent-free reactions afforded good yields of N-dehydroabietic imines and α-aminophosphonates although the strong space block of dehydroabietylamine to amino group. The green approaches resulted negligible waste and the reactions were environment friendly without using noxious solvents.

Keywords:

• N-Dehydroabietic
• Aminoarylmethylphosphonates
• Solvent-free

Acknowledgement

We thank the Chinese government “The 10th 5-year programme to tackle key problems” foundation for the financial support.