Triterpene and flavone glycosides from Anchusa undulata subsp. hybrida

Abstract

A novel triterpene glycoside, undulatoside (1), which is characterised as 3-O-(β-D-glucopyranosyl)-29-O-(β-D-glucopyranosyl)-2α,23-dihydroxyolean-12-en-28-oic acid, was isolated from Anchusa undulata subsp. hybrida and its structure was deduced by spectral data. In addition to undulatoside, seven known triterpene glycoside and a flavonoid glycoside were also isolated for the first time from this plant. The structures have been identified by spectroscopic and chemical methods. The antimicrobial activities of all extracts of the plant were investigated by disc diffusion method.

Keywords:

• Anchusa undulata subsp. hybrida
• Boraginaceae
• undulatoside
• triterpene glycoside
• flavonoid glycoside
• antimicrobial activity

Acknowledgements

The authors greatly acknowledge Assoc. Prof. İhsan Yaşa for antimicrobial analysis and Ege University Research Fund Accountancy (2002/FEN/045) of Turkey for financial support.