A new steroidal glycoside and fatty acid esters from the stem bark of Tectona grandis Linn.

Abstract

The phytochemical investigation of the bark of Tectona grandis Linn. afforded a new steroidal glycoside identified as β-sitosterol-β-D-[4′-linolenyl-6′-(tridecan-4′′′-one-1′′′-oxy)] glucuranopyranoside and three new fatty esters, 7′-hydroxy-n-octacosanoyl n-decanoate, 20′-hydroxy eicosanyl linolenate and 18′-hydroxy n-hexacosanyl n-decanoate, along with the known compounds n-docosane, lup-20(29)-en-3β-ol, betulinic acid and stigmast-5-en-3-O-β-D-glucopyranoside. Their stereostructures have been elucidated on the basis of spectral data analyses and chemical reactions.

Keywords:

• Tectona grandis
• Verbenaceae
• steroidal glycoside
• fatty acid esters
• structure elucidation

Acknowledgement

The authors are thankful to the Head, Regional Sophisticated Center, Central Drug Research Institute, Lucknow for recording mass spectral data of the plant.