Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 24, 2010 - Issue 3
Submit an article Journal homepage
139
Views
6
CrossRef citations to date
0
Altmetric
Original Articles

Isolation of a new glycoside from starfish, Asterias amurensis Lutken, and its stimulation activity on the proliferation of the UMR106 cell

Hong-Wei Liu Key Laboratory of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, 13 Beiertiao, Zhongguancun, Beijing 100080, PR China; Life Science Division, Graduate School at Shenzhen, Tsinghua University, The University Town, Shenzhen 518055, PR ChinaCorrespondence[email protected]
,
Jian-Kuan Li School of Pharmaceutical Sciences, Shanxi Medical University, Taiyuan 030001, PR China
,
Da-Wei Zhang Department of Natural Product Chemistry, Shenyang Pharmaceutical University, Wenhua-Road 103, Shenyang 110016, PR China
,
Jing-Chao Zhang College of Chemistry & Environmental Science, Hebei University, Baoding 071002, PR China
,
Xue Zhang Department of Natural Product Chemistry, Shenyang Pharmaceutical University, Wenhua-Road 103, Shenyang 110016, PR China
,
Xiao-Hong Song Key Laboratory of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, 13 Beiertiao, Zhongguancun, Beijing 100080, PR China
,
Ying Xia Key Laboratory of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, 13 Beiertiao, Zhongguancun, Beijing 100080, PR China
,
Nai-Li Wang Department of Natural Product Chemistry, Shenyang Pharmaceutical University, Wenhua-Road 103, Shenyang 110016, PR China
,
Xin-Sheng Yao Department of Natural Product Chemistry, Shenyang Pharmaceutical University, Wenhua-Road 103, Shenyang 110016, PR China
&
Guo-Ping Cai Life Science Division, Graduate School at Shenzhen, Tsinghua University, The University Town, Shenzhen 518055, PR China
 show all
Pages 294-299 | Received 21 Jan 2008, Accepted 23 May 2008, Published online: 05 Feb 2010
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

A new glycoside compound (1) was isolated from the starfish Asteria amurensis Lutken. The structure for compound 1 was identified as 1-O-{β-D-quinovopyranosyl–(1-2)-β-D-fucopyranosyl-(1-4)-[β-D-fucopyranosyl(1-2)] β-D-quinovopyranosyl}-butanol by extensive NMR experiments as well as chemical evidence. The effects of compound 1 on UMR106 cell proliferation were screened by MTT assay. The results indicate that compound 1 (0.01–100 µM) significantly promotes osteoblastic proliferation.

Acknowledgements

This work was supported by grants from the China Postdoctoral Science Foundation (2005037065) and the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, China.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 861.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.