Antithrombotic flavonoids from the faeces of Trogopterus xanthipes

Abstract

Chemical investigation of Trogopterus faeces has led to the isolation of seven flavonoids. Their structures were elucidated by chemical and spectral analyses. In an anticoagulative assay, three kaempferol coumaroyl rhamnosides had significant antithrombin activity. This is the first report on the occurrence of flavonoid glycosides in Trogopterus faeces.

Keywords:

• Trogopterus faeces
• kaempferol coumaroyl rhamnoside
• antithrombin activity

Acknowledgement

This work was supported by 2006 Great Basic Science Research Project of Jiangsu College and University (no. 06KJA36022).