A novel hexanordammarane glycoside from the leaves and stems of Panax quinquefolium L.

Abstract

One novel hexanordammarane glycoside, ginsenoside R₁₀, was isolated from the leaves and stems of Panax quinquefolium L. as a minor constituent. It is the first time that a hexanordammarane glycoside isolated from the plant of Panax quinquefolium L. Its structure was elucidated as 3-O-β-D-glucopyranosyl-3β, 12β-dihydroxy-22, 23, 24, 25, 26, 27-hexanordammarane-20-one (1), by the combination analysis of one-dimensional NMR, two-dimensional NMR and mass spectrometry.

Keywords:

• Panax quinquefolium L.
• hexanordammarane
• ginsenoside R₁₀

Acknowledgements

This work was financially supported by the Supporting Program of the ‘Eleventh Five-year Plan’ for Sci & Tech Research of China (No. 2007BAI38B04). We are grateful to Professor Zhang Jing-min for identification of the plant material. We are also very grateful to Chun-Yu Wang (Key Laboratory for Supramolecular Structure and Materials of Ministry of Education, Jilin University) for the measurement of NMR.