Two new alkaloid galactosides from the kernel of Prinsepia uniflora

Abstract

Two new alkaloid galactosides have been isolated from the kernel of Prinsepia uniflora. Their structures were elucidated as 5-[(α-D-galactopyranosyloxy) methyl]-1H-pyrrole-2-carbaldehyde (1) and 6-[(α-D-galactopyranosyloxy) methyl]-3-pyridinol (2) by various spectroscopic means including HR-ESI-MS, IR, 1D and 2D NMR. The determined structures were characterized with a unit of galactose which is rarely seen in the previously isolated pyrrole and pyridinol compounds.

Keywords:

• Prinsepia uniflora
• alkaloid galactoside
• 5-[(α-D-galactopyra-nosyloxy) methyl]-1H-pyrrole-2-carbaldehyde
• 6-[(α-D-galactopyranosyl-oxy) methyl]-3-pyridinol

Acknowledgements

We show our grateful thanks to Dr Xiaopo Zhang for his kindly help in giving important suggestions. Thankfulness should also be given to financial support from Chinese Traditional Medicine Researches of Special Projects (No. 200807020).