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Natural Product Research
Formerly Natural Product Letters
Volume 27, 2013 - Issue 8
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Research Article

A new bromobenzyl methyl sulphoxide from marine red alga Symphyocladia latiuscula

Xiuli Xu School of Ocean Sciences, China University of Geosciences, Beijing 100083, P.R. ChinaCorrespondence[email protected]
,
Liyuan Yin School of Ocean Sciences, China University of Geosciences, Beijing 100083, P.R. China
,
Yinghui Wang Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100190, P.R. China
,
Shuyuan Wang College of Physics and Chemistry, Hebei Normal University of Science and Technology, Qinhuangdao 066004, P.R. China
&
Fuhang Song Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100190, P.R. ChinaCorrespondence[email protected]
Pages 723-726 | Received 30 Sep 2011, Accepted 22 Apr 2012, Published online: 12 Jun 2012
 
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Abstract

A new bromophenol, 2,3,6-tribromo-4,5-dihydroxybenzyl methyl sulphoxide, was isolated from the EtOH extract of the marine alga Symphyocladia latiuscula. Its structure was confirmed by spectroscopic methods (1D- and 2D-NMR, HR-ESI-MS). This new bromophenol showed moderate antifungal activity against Candida albicans with MIC value of 37.5 µg mL−1.

Acknowledgements

This study was supported by the Fundamental Research Funds for the Central Universities, Research Fund for the Doctoral Program of Higher Education of China (200804911002), National Natural Science Foundation of China (30901849) and Science and Technology Planning Project of Zhejiang Province, China (2009C33004).

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