Comparative study of the chemical composition and biological activities of Magnolia grandiflora and Magnolia virginiana flower essential oils

Abstract

The biological activities and the determined major volatile components in the Magnolia grandiflora and M. virginiana flowers extracts were compared. Volatile components were detected in the essential oil by dynamic headspace sampling (HS). 2-Phenylethanol (40% and 61%) was found as the main constituent in the essential oil and HS samples of M. virginiana, respectively. In the M. grandiflora oil sample, (E,E)-farnesol (18%) and 2-phenylethanol (10%) were found as main constituents, whereas germacrene D (17%) and β-bisabolene (17%) were the main components of the HS sample. The essential oil in M. virginiana displayed a moderate antioxidant activity relative to vitamin E, whereas both essential oils were active against human lung carcinoma and breast carcinoma cell lines, even at concentrations higher than 200 µg mL⁻¹.

Keywords:

• Magnolia grandiflora L.
• Magnolia virginiana L.
• headspace volatiles
• essential oil
• antioxidant
• anticancer
• GC-MS

Acknowledgements

Dr Mohamed A. Farag thanks the Alexander von Humboldt foundation, Germany, for financial support.