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Natural Product Research
Formerly Natural Product Letters
Volume 27, 2013 - Issue 20
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Research Article

New alkylated benzoquinone from Iris nepalensis

Mudasir A. TantryNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, MS38677, USA;Drug Standardisation Research Unit, Regional Research Institute of Unani Medicine, NaseemBagh, Srinagar, 190006, KashmirIndiaCorrespondence[email protected]
,
Khalid GhazanfarDrug Standardisation Research Unit, Regional Research Institute of Unani Medicine, NaseemBagh, Srinagar, 190006, KashmirIndia
&
Ummer R. ZargarCentre of Research for Development, University of Kashmir, Srinagar, 190006, KashmirIndia
Pages 1832-1836 | Received 09 May 2012, Accepted 21 Nov 2012, Published online: 31 Jan 2013
 
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Abstract

Chemical investigation of chloroform extract of rhizomes of Iris nepalensis yielded new alkylated 1,4-benzoquinone derivative (1). The structure of Compound 1 was established by analysis of spectroscopic data. Compound 1 was evaluated for cytotoxic activities against human cancer cell lines A549, HL-60, HCT116 and ZR-75. Compound 1 showed least cytotoxicity against HL-60, HCT116 and ZR-75-30.

Acknowledgement

MT thanks the Center for Scientific and Industrial Research (CSIR), New Delhi, India, for financial assistance for his Postdoctoral Research.

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