Abstract
A new C30 linear polyacetylene compound designated petroacetylene (1) has been isolated from the marine sponge Petrosia solida Hoshino 1981, collected off the coast of Amami-Oshima, Kagoshima Prefecture, Japan. The structure was elucidated on the basis of spectroscopic data and chemical means. Petroacetylene (1) inhibited blastulation of starfish embryos at a concentration of 3.1 μg mL− 1 or greater.
Acknowledgements
The authors thank Captain A. Goh and the crew of R/V Toyoshio-Maru of Hiroshima University, for the help in the collection of sponge samples, and Professor Patricia R. Bergquist, The University of Auckland, New Zealand, for the identification of the sponge specimen. This work was supported in part by JSPS KAKENHI (Grant Nos 21510235 and 23658102).