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Natural Product Research
Formerly Natural Product Letters
Volume 28, 2014 - Issue 19
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Short Communication

A new C19-diterpenoid alkaloid from the roots of Aconitum duclouxii

Tian-Peng YinKey Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, Yunnan, 650091, P.R. China
,
Le CaiKey Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, Yunnan, 650091, P.R. China
,
Hao ZhouKey Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, Yunnan, 650091, P.R. China
,
Xiu-Fang ZhuKey Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, Yunnan, 650091, P.R. China
,
Yang ChenDepartment of Pharmaceutical, Zunyi Medical College Zhuhai Campus, Zhuhai, Guangdong, 519041, P.R. China
&
Zhong-Tao DingKey Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, Yunnan, 650091, P.R. ChinaCorrespondence[email protected]
Pages 1649-1654 | Received 17 Feb 2014, Accepted 20 May 2014, Published online: 20 Jun 2014
 
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Abstract

A new C19-diterpenoid alkaloid, ducloudine F (1), was obtained from the roots of Aconitum duclouxii, along with eight known alkaloids (2–9) isolated from this species for the first time. Their structures were established on the basis of extensive spectroscopic analyses. The antimicrobial activities of these compounds were investigated.

Acknowledgements

This project was supported by a grant from the Program for Changjiang Scholars and Innovative Research Team in University (IRT13095) and grants from the Natural Science Foundation of China (21002084, 21162046).

Notes

1. These authors contributed equally to this study.

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