Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 29, 2015 - Issue 3
293
Views
22
CrossRef citations to date
0
Altmetric
Short Communication

Isolation, structural elucidation and in vitro antioxidant activity of compounds from chloroform extract of Cedrus deodara (Roxb.) Loud.

, &
Pages 268-273 | Received 01 Jun 2014, Accepted 30 Jun 2014, Published online: 07 Aug 2014
 

Abstract

This study was designed to isolate, characterise and explore in vitro antioxidant potential of compounds from the chloroform extract of Cedrus deodara wood belonging to Pinacae family. We have investigated the in vitro free radical scavenging activity of isolated compounds by measuring total antioxidant capacity (TAC) and reducing power ability. From the chloroform extract five sesquiterpenes namely atlantone, himaphenolone, atlantolone, deodardione and atlantone-2,3-diol were identified. Himaphenolone and deodardione from the chloroform extract of this plant have been isolated for the first time. A marked dose-dependent reducing power and strong TAC were found in favour of himaphenolone and atlantone-2,3-diol, respectively. Moreover, deodardione and atlantolone also exhibit good antioxidant potentials. However, atlantone has showed least antioxidant activity. In conclusion, the chloroform extract of C. deodara exhibited significant antioxidant potential mainly due to the presence of sesquiterpenes which may be responsible for various pharmacological activities of this plant.

Acknowledgements

The authors would like to thank Prof. (Dr) Umesh Kumar Singh, Dr Anurag, Dr Manish Sinha and Mr Mandeep Kumar Arora for their technical support. The authors are also truly grateful to the Central Drug Research Institute, Lucknow, for providing the spectral analysis of the compounds.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 861.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.