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Natural Product Research
Formerly Natural Product Letters
Volume 28, 2014 - Issue 20
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Articles

Synthesis of 8-methyl-1-tetralone, a potential intermediate for ( ± )-platyphyllide

Po S. PoonCentro de Química, Instituto Venezolano de Investigaciones Científicas (IVIC), Apartado-21827, Caracas, 1020A, Venezuela
,
Liadis BedoyaCentro de Química, Instituto Venezolano de Investigaciones Científicas (IVIC), Apartado-21827, Caracas, 1020A, Venezuela
,
Gabriel J. ChurioCentro de Química, Instituto Venezolano de Investigaciones Científicas (IVIC), Apartado-21827, Caracas, 1020A, Venezuela
&
Ajoy K. BanerjeeCentro de Química, Instituto Venezolano de Investigaciones Científicas (IVIC), Apartado-21827, Caracas, 1020A, VenezuelaCorrespondence[email protected]
Pages 1747-1753 | Received 23 Apr 2014, Accepted 13 Jul 2014, Published online: 11 Aug 2014
 
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Abstract

An alternative method for the synthesis of the 8-methyl-1-tetralone from the commercially available 5-methoxy-1-tetralone has been developed. The transformation involves eight steps and affords an overall yield 25%.

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