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Natural Product Research
Formerly Natural Product Letters
Volume 29, 2015 - Issue 9
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Articles

A new briarane-type diterpenoid from the South China Sea Gorgonian Dichotella gemmacea

Jian-Fan SunInstitute of Environment and Ecology, Jiangsu University, Zhenjiang212013, P.R. China;CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou510301, P.R. ChinaView further author information
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Bin YangCAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou510301, P.R. ChinaView further author information
,
Xue-Feng ZhouCAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou510301, P.R. ChinaView further author information
,
Xian-Wen YangCAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou510301, P.R. ChinaView further author information
,
Lishu WangJilin Provincial Academy of Chinese Medicine Sciences, Changchun130021, P.R. ChinaView further author information
&
Yonghong LiuCAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou510301, P.R. ChinaCorrespondence[email protected]
View further author information
Pages 807-812 | Received 29 Jul 2014, Accepted 08 Nov 2014, Published online: 03 Dec 2014
 
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Abstract

One new briarane-type diterpenoid, dichotellide V (1), along with four known analogues, gemmacolide N (2), dichotellide J (3), junceelin A (4) and junceellolide A (5), was isolated from the South China Sea gorgonian Dichotella gemmacea. All of the isolated compounds (1–5) were established by comprehensive analysis of the spectral data, especially 1D and 2D NMR (HMQC and HMBC) spectra. The cytotoxic activities of these compounds were evaluated.

Additional information

Funding

This study was supported by the National Basic Research Program of China (973)' Project [2010CB833800] and [2011CB915503]; the National High Technology Research and Development Program (863 Program, [2012AA092104]); the National Natural Science Foundation of China [31200317], [31270402], [21172230], [20902094], [41176148], and [21002110]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11030403]; and Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012-D01-001].

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