Abstract
Fuzhuan brick-tea (FBT) is unique for a fungal fermentation stage in its manufacture process and is classified in dark tea. A new acylated flavonol glycoside, kaempferol 3-O-[E-p-coumaroyl-(→2)][α-l-arabinopyranosyl-(1→3)][α-l-rhamnopyranosyl(1→6)]-β-d-glucopyranoside, which was trivially named as camellikaempferoside A (1), was isolated from FBT along with camelliquercetiside C (2). Their structures were unambiguously elucidated by combination of spectroscopic and chemical methods. Compound 1 showed anti-proliferative activity against MCF-7 and MDA–MB-231 cells with IC50 values of 7.83 and 19.16 μM, respectively.
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Supplemental data
Supplemental data for this article can be accessed at http://dx.doi.org/10.1080/14786419.2015.1136911.
Acknowledgments
We thank Mr. Xin-Yi Liu and Mr. Mao-Qiang An of Yiyang Fu Cha Industry Development Co. Ltd, for supplying of the tea samples, and Mr. Yu-Song Wang, University of Science and Technology of China, Chinese Academy of Sciences, for NMR measurements.
Funding
This work was supported by National Modern Agriculture Technology System [grant number CARS-23]; National Natural Science Foundations of China [grant number 31300426], [grant number 31101335], [grant number 31471720].