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Natural Product Research
Formerly Natural Product Letters
Volume 30, 2016 - Issue 23
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Short Communications

Chemical composition and antioxidant, antibacterial activity of Cirsium rivulare (Jacq) All. roots

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Pages 2730-2733 | Received 05 Nov 2015, Accepted 20 Dec 2015, Published online: 28 Jan 2016
 

Abstract

The mixture of three phytosterols (campesterol, stigmasterol and β-sitosterol), β-sitosterol 3-O-glucoside and syringin were isolated from hexane and methanol extract of Cirsium rivulare roots after chromatographic separation. The main component of the source was syringin which was obtained with the yield 0.08% of the dry source. In hexane extract, the qualitative and quantitative composition of fatty acids was determined. The predominant component was linoleic acid (23.31 mg/g of extract). The extracts showed antioxidant activity. The ability to scavenge DPPH• free radical was in correlation with appointed total phenol content. The not-defatted methanolic extract was the most active. Hexane and defatted methanol extracts showed moderate antibacterial activity against G(+) and G(−) strains with MIC and MBC ranged from 25 to 200 μg/mL.

Funding

The work was supported by the Medical University of Bialystok [grant number 143-12788 F].

Disclosure statement

No potential conflict of interest was reported by the authors.

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