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Natural Product Research
Formerly Natural Product Letters
Volume 30, 2016 - Issue 20
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Research Articles

One new berberine from the branches and leaves of Polyalthia obliqua Hook.f. & Thomson

Li-Jun WuKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Cai-Juan ZhengKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Liu-Kai WangKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Chang-Ri HanKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Xiao-Ping SongKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, ChinaCorrespondence[email protected]
,
Guang-Ying ChenKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Xue-ming ZhouKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Shou-yuan WuKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Xiao-bao LiKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Meng BaiKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Chun-xin LiuKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
&
Jun YaoKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
 show all
Pages 2285-2290 | Received 25 Nov 2015, Accepted 19 Feb 2016, Published online: 19 Apr 2016
 
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Abstract

One new alkaloid consanguine B (1), together with 10 known alkaloids (2–11), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua Hook.f. & Thomson collected in the Hainan Province, China. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All compounds were evaluated for their cytotoxic activities. Compound 1 showed weak cytotoxic activities against Hela and MCF-7 human cancer cell lines.

Funding

This work was supported financially by the National Natural Science Foundation of China [grant number 81160391], [grant number 21166009], [grant number 81360478]; the Ministry of Science and Technology of China [International S&T cooperation Program of China (ISTCP)] [grant number 2014DFA40850].

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