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Natural Product Research
Formerly Natural Product Letters
Volume 30, 2016 - Issue 20
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Research Articles

A new cycloartane triterpene glycoside from Souliea vaginata

Hai-Feng WuKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China
,
Gang ZhangKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China;College of Pharmacy and Shaanxi Provincial Key Laboratory for Chinese Medicine Basis & New Drugs Research, Shaanxi University of Chinese Medicine, Xi’an, P.R. China
,
Mei-Chun WuKey Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources, Department of Chemistry & Chemical Engineering, Huaihua University, Huaihua, P.R. China
,
Wen-Ting YangKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China;College of Pharmacy and Shaanxi Provincial Key Laboratory for Chinese Medicine Basis & New Drugs Research, Shaanxi University of Chinese Medicine, Xi’an, P.R. China
,
Guo-Xu MaKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China
,
Di-Zhao ChenKey Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources, Department of Chemistry & Chemical Engineering, Huaihua University, Huaihua, P.R. China
,
Xu-Dong XuKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China
,
Qiong-Yu ZouKey Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources, Department of Chemistry & Chemical Engineering, Huaihua University, Huaihua, P.R. China;Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. ChinaCorrespondence[email protected]
&
Wei-Cheng HuJiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection/Jiangsu Key Laboratory for Eco-Agricultural Biotechnology around Hongze Lake, Huaiyin Normal University, Huaian, P.R. ChinaCorrespondence[email protected]
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Pages 2316-2322 | Received 28 Dec 2015, Accepted 13 Mar 2016, Published online: 06 Apr 2016
 
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Abstract

A new cycloartane-type triterpene glycoside, namely soulieoside M (1), and one known compound, beesioside I (2), were isolated from the ethanolic extract of the rhizomes of Souliea vaginata. Their structures were determined spectroscopically and compared with previously reported spectral data. Compounds 1 and 2 were evaluated for their cytotoxic activities against three human cancer cell lines.

Funding

This work was supported by the ‘Program for Innovative Research Team in IMPLAD’ and the technological large platform for comprehensive research and development of new drugs in the Twelfth Five-Year ‘Significant New Drugs Created’ Science and Technology Major Projects [grant number 2012ZX09301-002-001-026]; New Scientific and Technological Star Program of Shaanxi Province [grant number 2012KJXX-44]; Science and Technology Project of Hunan Province [grant number 2012FJ4293]; University Industrialization Cultivation Project of Hunan Province [grant number 11CY013].

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