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Natural Product Research
Formerly Natural Product Letters
Volume 31, 2017 - Issue 9
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Research Articles

One new lignan derivative from the Combretum alfredii Hance

Meng BaiKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Li-Jun WuKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Yue CaiKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Shou-Yuan WuKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Xiao-Ping SongKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Guang-Ying ChenKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China
,
Cai-Juan ZhengKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, ChinaCorrespondence[email protected]
[email protected]
&
Chang-Ri HanKey Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China;Hainan Institute of Science and Technology, Haikou, People’s Republic of ChinaCorrespondence[email protected]
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Pages 1022-1027 | Received 09 Aug 2016, Accepted 14 Nov 2016, Published online: 14 Dec 2016
 
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Abstract

One new lignan derivative 2,3-dimethyl-4-(4-methoxyphenyl)-6,7-dihydroxynaphthalene (1), together with five known compounds (2–6), were isolated from ethanol extract of the branches and leaves of Combretum alfredii Hance collected in Hainan Province, China. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compounds 1, 2, 5 and 6 were isolated from the genus of Combretum for the first time. All compounds were evaluated for their antibacterial activities. Compounds 1 and 2 showed significant antibacterial activities against six pathogenic bacteria.

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