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Natural Product Research
Formerly Natural Product Letters
Volume 31, 2017 - Issue 13
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Research Articles

Two new flavans from the roots of Dianella ensifolia (L.) DC

Ben-Qin TangDepartment of Medical Science, Shunde Polytechnic, Shunde, ChinaCorrespondence[email protected]
,
Shu-Sheng HuangDepartment of Medical Science, Shunde Polytechnic, Shunde, China
,
Ye-Er LiangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR, China
,
Jian-Bo SunDepartment of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, China
,
Yan MaDepartment of Medical Science, Shunde Polytechnic, Shunde, China
,
Bao ZengDepartment of Medical Science, Shunde Polytechnic, Shunde, China
,
Simon Ming-Yuen LeeState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR, China
&
Jian-Lin LuDepartment of Medical Science, Shunde Polytechnic, Shunde, ChinaCorrespondence[email protected]
 show all
Pages 1561-1565 | Received 15 Dec 2016, Accepted 14 Jan 2017, Published online: 30 Jan 2017
 
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Abstract

Two new flavans, named (2S)-2′,4′-dihydroxy-7-methoxy-8-methylflavan (1) and (2S)-2′-hydroxy-4′,7-dimethoxy-8-methylflavan (2) were isolated from the roots of Dianella ensifolia. Their structures were elucidated by extensive spectroscopic measurements and comparison with data reported in literatures. Compounds 1 and 2 displayed cytotoxic effects against cancer cell lines MDA-MB-231, B16-F10, HCT116 and A549.

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