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Natural Product Research
Formerly Natural Product Letters
Volume 32, 2018 - Issue 4
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Research Articles

Four new anthraquinones from a soil actinomycete Streptomyces sp. WS-13394 and their bioactivities

Zhaoyuan WuHubei Biopesticide Engineering Research Centre, Hubei Academy of Agricultural Sciences, Wuhan, P. R. China
,
Yani ZhangHubei Biopesticide Engineering Research Centre, Hubei Academy of Agricultural Sciences, Wuhan, P. R. China
,
Wei FangHubei Biopesticide Engineering Research Centre, Hubei Academy of Agricultural Sciences, Wuhan, P. R. China
,
Liqiao ShiHubei Biopesticide Engineering Research Centre, Hubei Academy of Agricultural Sciences, Wuhan, P. R. ChinaCorrespondence[email protected]
&
Zhongyi WanHubei Biopesticide Engineering Research Centre, Hubei Academy of Agricultural Sciences, Wuhan, P. R. ChinaCorrespondence[email protected]
Pages 412-417 | Received 23 Jan 2017, Accepted 29 Mar 2017, Published online: 25 Apr 2017
 
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Abstract

Further chemical study of secondary metabolites from the soil actinomycete Streptomyces sp. WS-13394 resulted in the isolation of four new alkylated anthraquinone analogues (5–8). Their structures were elucidated on the basis of extensive spectroscopic analysis, including HR-ESI-MS, 1D and 2D NMR. The new compounds, together with analogues obtained before (1–4), were tested for their in vitro cytotoxicity against Huh-7 and SGC-7901.

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