An optimized protocol for anthraquinones isolation from Rhamnus frangula L.

Abstract

Different from works described in the literature, which use expansive analytical methods to separation of anthraquinones derivatives (AQs), this communication reported a simple and inexpensive methodology to get them. In this way, the expensive commercial AQs: Chrysophanol, physcione and emodine were extracted from plant material (Rhamnus frangula L.) and isolated by classical column chromatography technique under optimised binary mobile phase gradients (CHCl₃ : AcOEt(a), a = 1 to 5%) in excellent yields.

Keywords:

• Optimised isolation
• column chromatography
• chrysophanol
• physcione
• emodine
• Rhamnus frangula L.