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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 12
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Short Communication

Efficient biosynthesis, analysis, solubility and anti-bacterial activities of succinylglycosylated naringenin

, , , , , & show all
Pages 1756-1760 | Received 25 Oct 2017, Accepted 14 Jan 2018, Published online: 15 Feb 2018
 

Abstract

A novel water-soluble flavonoid with good anti-bacterial activities, naringenin-6″-succl-7-O-glucoside (7-SGN), was synthesised. It was biotransformed from naringenin by Bacillus amyloliquefaciens FJ18 in aqueous miscible organic media, and characterised by LC-MS and NMR analysis. The solubility of 7-SGN in water was approximately 102 times higher than that of naringenin. These results demonstrated that both the water solubility and the anti-bacterial activity of 7-SGN were significantly improved.

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