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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 1
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Research Articles

A new dimeric secoiridoids derivative, japonicaside E, from the flower buds of Lonicera japonica

Wen GeNanjing University of Chinese Medicine, Nanjing, China;Jiangsu Kanion Pharmaceutical Co. Ltd., Jiangsu Lianyungang, China;State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Jiangsu Lianyungang, China
,
Hai-Bo LiJiangsu Kanion Pharmaceutical Co. Ltd., Jiangsu Lianyungang, China;State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Jiangsu Lianyungang, China
,
Hui FangJiangsu Kanion Pharmaceutical Co. Ltd., Jiangsu Lianyungang, China;State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Jiangsu Lianyungang, China
,
Biao YangJiangsu Kanion Pharmaceutical Co. Ltd., Jiangsu Lianyungang, China;State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Jiangsu Lianyungang, China
,
Wen-Zhe HuangJiangsu Kanion Pharmaceutical Co. Ltd., Jiangsu Lianyungang, China;State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Jiangsu Lianyungang, China
,
Wei XiaoJiangsu Kanion Pharmaceutical Co. Ltd., Jiangsu Lianyungang, China;State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Jiangsu Lianyungang, ChinaCorrespondence[email protected]
&
Zhen-Zhong WangJiangsu Kanion Pharmaceutical Co. Ltd., Jiangsu Lianyungang, China;State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Jiangsu Lianyungang, ChinaCorrespondence[email protected]
 show all
Pages 53-58 | Received 25 Sep 2017, Accepted 16 Jan 2018, Published online: 03 Mar 2018
 
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Abstract

A new dimeric secoiridoids derivative, named japonicaside E, together with six known compounds were isolated from the flower buds of Lonicera japonica. The structures of these compounds were elucidated by the analyses of mass spectrometry and NMR spectroscopy. All compounds were evaluated for anti-inflammatory activity in vitro.

Acknowledgements

We thank Tao Jiang in Jiangsu Kanion Pharmaceutical Co. Ltd, State Key Lab of New-Tech for Chinese Medicine Pharmaceutical Process for helping to evaluate the anti-inflammatory activity of the isolated compounds.

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