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Abstract
One new lignan derivative 2,3-dimethyl-4-(4′-hydroxy-3′,5′-dimethoxyphenyl)-6-hydroxy-7-methoxy-naphthalene (1), together with four known analogues (2-5), were isolated from acetone extract of the fruiting bodies of Ganoderma lipsiense collected in the Hainan Province, China. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compound 1 showed insecticidal activity against newly hatched karvae of Helicoverpa armigera Hubner. Compounds 1-5 showed moderate antibacterial activity against Staphylococcus aureus with the same MIC value of 1.25 μg/mL.
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Disclosure statement
No conflict of interest was reported by the authors.
Additional information
Funding
This work was supported by the Foundation for the National Natural Science Foundation of China (Nos. 21662012, 21462015 and 31760093), Program for Innovative Research Team in University (No. IRT-16R19), Hainan Province Natural Science Foundation of Innovative Research Team Project (No. 2016CXTD007).