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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 6
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Short Communications

Antibacterial and antifungal properties of crude extracts and isolated compounds from Lychnophora markgravii

Alvaro José Hernández TascoVegetal biology department, State University of Campinas (UNICAMP), Campinas, Brazil; Correspondence[email protected]
,
Román Yesid Ramírez RuedaVegetal biology department, State University of Campinas (UNICAMP), Campinas, Brazil;
,
Carlos José AlvarezVegetal biology department, State University of Campinas (UNICAMP), Campinas, Brazil; ;Microbiology department, University of Pamplona, Pamplona, Colombia.
,
Fabiana Terezinha SartoriChemistry department, São Paulo University/Ribeirão Preto (RP-USP), Ribeirão Preto, Brazil;
,
Ana Claudia B. C. SacilottoChemistry department, São Paulo University/Ribeirão Preto (RP-USP), Ribeirão Preto, Brazil;
,
Izabel Yoko ItoDepartments of Physics and Chemistry, and Clinical, Toxicological and Bromatological Analysis, São Paulo University/Ribeirão Preto (RP-USP), Ribeirão Preto, Brazil;
,
Walter VichnewskiDepartments of Physics and Chemistry, and Clinical, Toxicological and Bromatological Analysis, São Paulo University/Ribeirão Preto (RP-USP), Ribeirão Preto, Brazil;
&
Marcos José SalvadorVegetal biology department, State University of Campinas (UNICAMP), Campinas, Brazil;
show all
Pages 863-867 | Received 13 Mar 2018, Accepted 17 Jul 2018, Published online: 16 Nov 2018
 
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Abstract

Antimicrobial activity of dichloromethane and ethanol extracts and five compounds: pinostrobin (I), pinocembrin (II), tectochrysin (III), galangin 3-methyl ether (IV) and tiliroside (V) isolated from Lychnophora markgravii aerial parts against fifteen microorganisms was determined. The structures of these compounds were elucidated based on ESI-MS and NMR spectroscopic data. Both extracts showed antimicrobial activity against several tested microorganisms. Pinostrobin, tectochrysin and galangin 3-methyl ether showed the strongest antibacterial and antifungal effects.

Graphical Abstract

Acknowledgements

The authors are grateful to Prof. João Semir (UNICAMP, SP, Brazil) for identifying the plant and to CNPq, CAPES and FAPESP for financial support.

Disclosure statement

The authors declare no conflict of interest.

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