Integrated extraction and purification of total bioactive flavonoids from Toona sinensis leaves

Abstract

An integrated procedure was developed to extract and purify total flavonoids from Toona sinensis leaves for the first time, in which pressurized liquid extraction was performed in tandem with HPD100 macroporous resin column. Consequently, the total flavonoids can be extracted using 10% EtOH, and the recovery and purity of total flavonoids was 71.05% and 66.60%. Moreover, products of high quality were obtained in an environmentally friendly process with lower consumption of time and solvent. The results demonstrated that the integrated extraction-adsorption procedure was an efficient process for the preparation of total bioactive flavonoids from Toona sinensis leaves.

Graphical Abstract

Keywords:

• Toona sinensis leaves
• bioactive flavonoids
• integrated extraction and purification
• pressurized liquid extraction
• macroporous resins

Disclosure statement

There are no conflicts of interest to declare.

Additional information

Funding

This study was supported by National Natural Science Foundation of China (81773855), Qing Lan Project (2016), and Six Talent Peaks in Jiangsu (YY-010).