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Abstract
A new protostane-type triterpenoid bearing an oxetane ring in the side-chain, named alisol W (1), has been obtained from the dried rhizome of Alisma plantago-aquatica subsp. orientale. The structure and absolute configuration of compound 1 was determined from extensive spectroscopic analysis. In addition, the vasorelaxant activity and the inhibition on 11β-HSD1 of compound 1 were also evaluated, however, it didn’t show remarkable effects.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was financially supported by the National Natural Science Foundation of the People’s Republic of China (grant number 31560103, 21572082 and U1602222) and the Personnel Training Project of Kunming University of Science and Technology, China (KKZ3201726045).