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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 2
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Research Articles

New flavonoid glycosides from seeds of Baccharoides anthelmintica

Yi LiuState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People’s Republic of China; ;University of Chinese Academy of Sciences, Beijing, People’s Republic of ChinaView further author information
,
Wen-qiong WangState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People’s Republic of China; View further author information
,
Tong ChenState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People’s Republic of China; View further author information
&
Li-jiang XuanState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People’s Republic of China; Correspondence[email protected]
View further author information
Pages 284-289 | Received 20 Jun 2018, Accepted 26 Sep 2018, Published online: 22 Dec 2018
 
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Abstract

Baccharoides anthelmintica is the most popular traditional Uighur medicines used for vitiligo. The chemical investigation of the seeds of B. anthelmintica led to the isolation of three new flavonoid glycosides (Vernosides A-C). Their structures were determined by comprehensive analysis of spectroscopic data including 1D and 2D NMR and HRMS data. Vernosides A-C were evaluated for their effects on tyrosinase activity, Vernoside B can enhance tyrosinase activity.

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Disclosure statement

No potential conflict interest was reported by the authors.

Additional information

Funding

This research was supported by a grant from the State Key Laboratory of Drug Research (NO.SIMM1601ZZ-03), the National Natural Science Foundation of China (NO. 81773863, No. 21702219).

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