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Abstract
Phytochemical investigation of the aerial parts of Micromeria persica led to the isolation of a new oleane type triterpenoid ester (1), together with six known compounds 2–7), comprising one phenyl ethanoid ester, one glycosylated flavonoid, two triterpenoids, and two steroids. Their structures were elucidated by interpretation of their one-dimensional and two-dimensional NMR spectra and completed by the analysis of the HRESIMS data. Compounds 1 and 3 were evaluated for their cytotoxic feature against human breast adenocarcinoma cell line (MDA-MB231) and human prostate cancer cell line (DU145). However, they did not show positive effect (IC50 > 75µM).
Acknowledgement
Financial support by the Shahid Beheshti University Research Council is gratefully acknowledged. Thanks are due to T. Hettich (School of Life Sciences, University of Applied Sciences, Institute for Chemistry and Bioanalytics, Muttenz) for the HRESIMS data.
Disclosure statement
No potential conflict of interest was reported by the authors.