Abstract
Two new cembrane diterpenoids, named populeuphrines A and B (1 and 2), together with three known analogues (3–5) were isolated from the resins of Populus euphratica. The planar structures and relative configurations of 1 and 2 were elucidated by detailed 1 D and 2 D NMR spectroscopic analyses. The absolute configurations of 1 and 2 were determined by X-ray diffraction analysis and quantum chemical computation. Biological activities of all the isolates against proliferation of human cancer cells and umbilical cord mesenchymal stem cells were evaluated.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the authors.