![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
A new bergamotane-type sesquiterpene, named axanthiol A (1), and six known compounds (2–7) were isolated from the rhizomes of Amomum villosum var. xanthioides. Their structures were established on the basis of extensive spectroscopic analysis and the absolute configuration of 1 was confirmed by the Mosher ester method. Moreover, all the isolates were evaluated for their effects on LPS-induced nitric oxide (NO) production, and compound 5 showed efficacious inhibitory activity with IC50 value of 34.81 μM.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was supported by the National Natural Science Foundation of China [No. 31600275 and 31600265]; the Natural Science Foundation of Guangxi Zhuang Autonomous Region of China [No. 2017GXNSFAA198077 and AD18281032]; and the Doctoral Starting Fund of Xinxiang Medical University [No. XYBSKYZZ201813].