Ustilaginoidin M₁, a new bis-naphtho-γ-pyrone from the fungus Villosiclava virens

Abstract

Ustilaginoidin M₁ (1), a novel bis-naphtho-γ-pyrone, was isolated from the cultures of the fungus Villosiclava virens which was the pathogen of rice false smut disease. Its structure was elucidated by spectroscopic analysis and by comparison of its physical and spectroscopic data with the literature. Compound 1 was tested for its cytotoxicity against five human cancer cell lines.

Keywords:

• Rice false smut
• Villosiclava virens
• ustilaginoidin M₁
• cytotoxic activity

Disclosure statement

All the authors declare no conflict of interest.

Additional information

Funding

This work was supported by the grants from the National Key R&D Program of China [grant number 2017YFD0201105], and the National Natural Science Foundation of China [grant numbers 31471729 and 31271996].