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Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 9
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Research Articles

Sesquiterpenoids from Pilea cavaleriei

Yong ZhouState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China; ;Beijing Pharmaceutical Group University of Staff and Workers, Beijing, China; View further author information
,
Ling-Yu LiInstitute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaView further author information
,
Xu YinState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China; View further author information
,
Qing-Ying ZhangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China; Correspondence[email protected]
View further author information
,
Hong LiangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China; Correspondence[email protected]
View further author information
&
Peng-Fei TuState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China; View further author information
Pages 1537-1543 | Received 18 Apr 2019, Accepted 09 Aug 2019, Published online: 05 Sep 2019
 
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Abstract

One new cis p-coumaroyl copaborneol-type sesquiterpenoid (1), together with its known trans isomer (2) and six other known p-coumaroyl humulane-type sesquiterpenoids (3–8), were isolated from the whole plants of Pilea cavaleriei. Their structures were determined by spectroscopic data. Compounds 1–4 exhibited moderate antimycobacterial activity against Mycobacterium tuberculosis H37Rv.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by the Beijing Natural Science Foundation (grant number 7132129).

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