Abstract
A novel hexanorditerpenoid, hedychin C (1), and a new diterpenoid, hedychin D (2), were isolated from the rhizomes of Hedychium forrestii. Their structures and absolute configurations were unambiguously established by means of extensive spectroscopic data (IR, UV, HRMS, and NMR) and electronic circular dichroism (ECD) calculations. This is the first report of naturally occurring labdane-type hexanorditerpenoid. Compound 1 was proved to have moderate cytotoxicity against XWLC-05 cell line with an IC50 value of 53.6 μM.
Acknowledgements
The authors are also grateful to Prof. Xiao-Qiong He (Kunming Medical University) for cytotoxic screening. The authors are also grateful to Kunming Institute of Botany, Chinese Academy of Sciences, for measuring IR, UV, HRMS, and NMR data, respectively.
Disclosure statement
No potential conflict of interest was reported by the authors.