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Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 15
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Short Communications

New Δ8,9-pregnene steroids isolated from the extremophile fungus Exophiala oligosperma

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Pages 2598-2601 | Received 10 May 2019, Accepted 15 Oct 2019, Published online: 01 Nov 2019
 

Abstract

Three pregnene steroids, two of them new, were isolated from ethyl-acetate partition of liquid-cultivation of the extremophyle fungus Exophiala oligosperma, found in a pH 1.5 hydrochloric acid aqueous solution. Spectroscopic studies using NMR and HRMS, allowed the identification of the molecular structures of both Δ8,9-pregnenes, still not described in the literature.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The authors would like to acknowledge funding from the São Paulo State Foundation (FAPESP; grant no. 2019/04900-2), the Brazilian National Council of Technological and Scientific Development (CNPq), and also the Coordenação de Aperfeiçoamento de Ensino Superior – Brasil (CAPES), Finance Code 001.

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