Polysaccharide from Caulerpa lentillifera: extraction optimization with response surface methodology, structure and antioxidant activities

Abstract

Ultrasonic-assisted extraction based on Response Surface Methodology was applied to isolate a polysaccharide (CLP) from Caulerpa lentillifera obtained in the South China Sea and the highest yield of the crude polysaccharide was 11.8%. CLP consisted of xylose, galactose, glucose and glucuronic acid in a molar ratio of 2.00: 1.00: 0.26: 0.04, with a molecular weight of 115 kDa. The content of uronic acids and sulfate groups in CLP was 14.10% and 27.40%, respectively. CLP presented good radical scavenging activities against O₂^·-, DPPH radical, while the scavenging activities against OH· and ABTS radical were not so satisfying.

Graphical Abstract

Keywords:

• Caulerpa lentillifera
• polysaccharide
• extraction
• structure
• antioxidant activities

Disclosure statement

No conflict of interest is declared by authors.

Additional information

Funding

This work was financially supported by the Key Research and Development Plan of Hainan Province (ZDYF2018232), the Project of Scientific Research Platform construction of Hainan University (ZY2019HN09), the National Science Foundation of China (21466011), and the Key Scientific and Technological Project of Haikou city (2010-084).