Solieritide A, a new polyketide from the red alga Solieria sp

Abstract

A new polyketide, solieritide A (1), along with six known ones (2–7), had been isolated from the red alga Solieria sp. The structures of these compounds were elucidated by spectroscopic analysis. The absolute configuration of 1 was determined by the method of X-ray diffraction. Compound 1 was a rare polyketide bearing benzopyrone ring fused with γ-butyrolactone. Compounds 2–7 were isolated from the red algae of genus Solieria for the first time. The antibacterial activities of 1–7 were also discussed.

Graphical Abstract

Keywords:

• Red alga
• solieria
• polyketide

Additional information

Funding

This work was financially supported by the National Key Research and Development Plan of China [grant Nos. 2018YFC0310900 and 2019YFD0901905]; the National Natural Science Foundation of China [grant Nos. 41876145, 21672084 and 81874292]; the Science and Technology Planning Project of Guangzhou (grant Nos. 201704030042 and 201710010088); the Natural Science Foundation of Guangdong Province. (grant No. 2018A030313152).